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. 2020 Jul 12;9(7):1676. doi: 10.3390/cells9071676

Figure 5.

Figure 5

(A) The PPI test at PND100 revealed two distinct behavioural phenotypes: MIA responsive (with the deficit in PPI) and MIA non-responsive (without the deficit) in male Sprague-Dawley offspring exposed to MIA. n = 17 in the control group, n = 9 in the MIA responsive group, n = 10 in the MIA non-responsive group. * p < 0.05 vs. control group. The results are presented as the individual data points of the percentage of PPI (%PPI) induced by each prepulse intensity with the means ± SEM. Data were calculated based on the average startle amplitudes (AVGs). (B) At PND120, the animals were additionally subjected to the acute challenge with LPS and 2 h later, the PPI was evaluated again. n = 4–10. * p < 0.05 vs. control + vehicle, ^ p < 0.05 vs. MIA non-responsive + vehicle, $ p < 0.05 vs. MIA responsive + LPS, & p < 0.05 vs. control + LPS. The results are presented as the means of the percentage of PPI (%PPI) induced by each prepulse intensity ± SEM. Data were calculated based on the average startle amplitudes (AVGs).