Table 2.
The effect of MIA on the prepulse inhibition of the acoustic startle response (PPI) in male Sprague-Dawley offspring at PND30 and PND60. n = 8–11 in each group. The results are presented as the means of the percentage of PPI (%PPI) induced by each prepulse intensity ± SEM. Data were calculated based on the average startle amplitudes (AVGs). * p < 0.05 vs. control group.
| Prepulse Intensity | Group | |||
|---|---|---|---|---|
| PND30 | PND60 | |||
| Control | MIA | Control | MIA | |
| 70 dB | 16.21 ± 9.67 | 25.08 ± 5.27 | 38.07 ± 3.95 | 44.66 ± 5.01 |
| 75 dB | 21.45 ± 8.45 | 43.85 ± 3.22 * | 58.60 ± 4.22 | 59.33 ± 4.02 |
| 80 dB | 33.93 ± 9.45 | 37.34 ± 5.69 | 52.00 ± 4.25 | 61.12 ± 3.53 |