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. 2020 Jul 9;9(7):1651. doi: 10.3390/cells9071651
ABC ATP-binding cassette 18F-FLT 18F-fluorothymidine NSCLC non-small cell lung carcinoma
Akt protein kinase B FGF fibroblast growth factor Oct-4 octamer binding protein 4
ALDH enzyme aldehyde
dehydrogenase
FOXO forkhead Box class O OER oxygen enhancement ratio
APLN angiopoietins, ephrins, apelin γ-H2AX phosphorylated Histone 2AX PDGF platelet-derived growth factor
ATM ataxia-telangiectasia mutated GS γ secretase PET positron emission tomography
ATR ataxia telangiectasia and Rad3-related protein GSIs γ-secretase inhibitors PlGF placental growth factor
Bcl-2 B-cell lymphoma 2 GSK-3β glycogen synthase kinase 3 beta PTEN phosphatase and tensin homolog
BCSC breast cancer stem cells HDAC histone deacetylases PI3K phosphatidylinositol 3-kinase
BSO buthionine ulfoximine HGF hepatocyte growth factor RAD51
CAFs cancer-associated fibroblasts Hh hedgehog signaling ROS reactive oxygen species
CAIX carbonic anhydrase IX HIF1a hypoxia-inducible factor-1a RBE relative biological effectiveness
CDC20 cell-division cycle protein 20 HR homologous repair ROS reactive oxygen species
CD133 prominin I ICB immune checkpoint blockade RT radiotherapy
CHART continuous hyperfractionated accelerated radiotherapy trial ICIs immune checkpoint inhibitors SBRT stereotactic body radiation therapy
chks checkpoints IL1β interleukine 1β SSEA stage-specific embryonic antigen
CHK1 checkpoint kinase 1 IL4 interleukine 4 SP side population
CHK2 checkpoint kinase 2 IL6 interleukine 6 TAMs tumor-associated macrophages
CSC cancer stem cells IL8 interleukine 8 TANs tumor-associated neutrophils
CTC circulating tumor cells IL10 interleukine 10 TIMPs endogenous metalloproteinase inhibitors
CXC C-X-C motif chemokines LET linear energy transfer TGF-ß transforming growth factor-ß
CXCL12
C-X-C
motif chemokine ligand 12 M1 classically activated macrophage TGF-ß1 transforming growth factor-ß1
DAHANCA Danish Head and Neck Cancer trial M2 alternatively activated macrophage TNF-α tumor necrosis factor-alpha
DAMPs damage associated
molecular patterns
MDSC myeloid-derived suppressor cells TICs tumor initiating cells
DCA dichloroacetate MiRNAs microRNAs TME tumor microenvironment
DDR DNA damage response MMPs matrix metalloproteases TRAIL Fas receptor and TNF-related apoptosis inducing ligand
DNA deoxyribonucleic Acid mRNA messenger RNA Treg regulatory T cells
DNA-PKc DNA-dependent protein kinase, catalytic subunit mTOR mammalian target of rapamycin TSCs tumor stem cells
DSBs double-strand breaks NFκB nuclear factor-κB UPR unfolded protein response
ECM extracellular matrix NHEJ non-homologous end joining UV ultraviolet
EGF epidermal growth factor NRF2 nuclear factor-erythroid 2 p45-related factor 2 VEGF vascular endothelial growth factor
EMT epithelial-mesenchymal transition NOD/SCID nonobese diabetic/severe combined immunodeficient Wnt wingless/integrated