Figure 1.

Gene expression profiling in 3D mucous membrane models after laser injury and treatment with a dexpanthenol-containing ointment in comparison with the placebo-treated control. (a) 3D mucous membrane models were harvested 3 days after laser treatment (100 mJ/cm²), and gene expression was measured using the Affymetrix^® Gene Chip Human Exon 2.0 ST microarray. Results of 3 experiments were pooled. (b) TaqMan real-time polymerase chain reaction (qRT-PCR) analysis of selected genes on day 3 after treatment. Mean values with standard error of the mean (SEM) of 3 independent experiments performed in duplicate are shown. From Ref. [54] with kind permission from S. Karger AG (www.karger.com/SPP).