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. 2020 Jul 1;10(7):988. doi: 10.3390/biom10070988

Table 6.

Major natural compounds, methodologies applied to determine the antioxidant activity, and the investigated applications of Rosmarinus officinalis (Lamiaceae) EOs.

Plant Organ Major Compounds (%) Antioxidant Activity Assay Investigated Properties References
leaves eucalyptol (15.2%), c
amphor (15.1%), and
β-pinene (11.0%)
DPPH Demonstrated the usefulness of the simplex-lattice mixture design method to optimize the antioxidant profile of an EO mixture (basil, marjoram, and rosemary). [126]
leaves α-pinene (14.69–20.81%),
eucalyptol (5.63–26.89%),
and camphor (4.02–24.82%)
DPPH Reported the antioxidant, antibacterial and chemical composition of rosemary EO extracted from plants collected in different regions. [48]
aerial parts eucalyptol (23.67%),
camphor (18.74%),
and borneol (15.46%)
DPPH
FRAP
Evaluated the chemical composition, antileishmanial, antibacterial, and antioxidant activities of rosemary EO. [189]
Leaves γ-cadinene (29.93%),
camphor (14.76–28.42%), and
eucalyptol (10.60–15.36%)
ABTS Used three different extraction methods (hydrodistillation, steam distillation, and supercritical CO2) and evaluated their chemical profile and antioxidant activity. [190]
Leaves eucalyptol (35.15–50.28%),
camphor (12.71–13.08%),
α-pinene (5.60–13.92%),
borneol (7.42–9.81%),
and α-terpineol (1.76–15.40%)
DPPH Described a method of rapeseed oil aromatization with rosemary. The EO aromatized was evaluated about the chemical composition and antioxidant activity. [5]
Leaves eucalyptol (11.33–37.29%),
camphor (8.81–40.35%), and
α-pinene (2.60–28.68%),
DPPH Evaluated the antioxidant activity of rosemary EO fractions obtained by molecular distillation and their effect on oxidative stability of sunflower oil. [188]
aerial parts camphor (14.80–42.50%),
eucalyptol (8.00–26.40%),
α-pinene (4.10–13.20%),
and myrcene (1.00–30.30%)
DPPH
FRAP
Extracted the EO from several cultivars of rosemary and evaluated their antioxidant activity. [178]
aerial part eucalyptol (35.32%),
(E)-caryophyllene (14.47%),
borneol (9.37%),
camphor (8.97%),
α-pinene (7.90%), and
α-thujone (6.42%)
DPPH
CAT
SOD
Evaluated the potential of rosemary EO as anti-hyperlipidemic, anti-hyperglycemic, and antioxidant. [191]
Leaves eucalyptol (42.86–46.76%),
camphor (16.26–23.42%),
α-pinene (6.37–9.19%),
camphene (2.27–4.37%),
and borneol (4.00–4.33%)
DPPH
FRAP
TBARS
Compared the chemical profile and antioxidant activity of the EOs of R. officinalis collected from China and Iran regions. [192]