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. 2020 Jul 11;9(7):1671. doi: 10.3390/cells9071671

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Purine DNA lesions measured by LC-MS/MS. (A) The levels (lesions/10⁶ Nu) of 5′R-cdG, 5′S-cdG, 5′R-cdA and 5′S-cdA in DNA samples isolated from CS3BE-wtCSA, CS3BE and CS3BE + Parkin cells. (B) The levels (lesions/10⁶ Nu) of total cPu and 8-oxo-Pu lesions in genomic DNA extracted from CS3BE-wtCSA, CS3BE and CS3BE + Parkin cells. The error bars represent the standard deviation of the mean, calculated from three independent samples. * denotes a statistically significant difference (p < 0.05) between the groups.