Table 4.

Values of minimal bactericidal concentration of Calendulae flos lyophilized extract and its chitosan delivery systems against selected Gram (+) bacteria, Gram (-) bacteria, and fungi.

Microorganism	Calendulae flos Lyophilized Extract	Lyophilized Extract + Chitosan 80/500 1:1	Lyophilized Extract + Chitosan 80/500 1:5	Lyophilized Extract + Chitosan 80/1000 1:1	Lyophilized Extract + Chitosan 80/1000 1:5	Chitosan 80/500	Chitosan 80/1000
	MBC (mg mL−1)
S. aureus	8	16	32	16	32	125	250
S. epidermidis	8	16	32	16	32	125	250
E. faecalis	32	64	125	16	125	125	250
E. faecium	32	64	125	32	125	125	250
S. pyogenes	64	64	125	32	125	125	250
E. coli	64	64	64	32 ↓	64	64	125
P. aeruginosa	4	8	64	16	32	125	125
P. acnes	16	8 ↓	8 ↓	4 ↓	125	125	125
Candida albicans	64	32 ↓	32 ↓	8 ↓	64	250	250

↓—the decrease in MBC value.