Table 2.

Identifying BC-associated discriminatory protein bands in serum samples. These include the integral ratio of Gaussian Function Energy Bands (GFEB), representing α-helix and β-sheet protein secondary structures, as well as the absorbance ratio of amide II (1556 cm⁻¹) to amide III (1295 cm⁻¹). Quantified values (in A.U.) of the average and range of spectral signatures taken from the control and BC samples. The optimal cutoff and the corresponding sensitivity, specificity, and p-values are also shown.

Signatures	Average ± st. Error		Range of Values		Cutoff Value	AUC	Sensitivity %	Specificity %	p-value
	Control	BC	Control	BC
α/β	2.61 ± 0.06	2.07 ± 0.09	2.27–2.95	1.77–2.62	2.25	0.96	90	90	1.4 × 10−4
I1556/ I1295	2.10 ± 0.01	2.24 ± 0.02	2.04–2.17	2.13–2.36	2.12	0.98	100	80	2.7× 10−5