Table 2. ABCB1 SNVs Associated With pCIA in the Discovery Cohort Using Logistic Regression Analysis.
SNV | CHR | Base pair | A1 | OR (95% CI) | P valuea | R2b | Source |
---|---|---|---|---|---|---|---|
rs1202179 | 7 | 87204279 | C | 3.79 (2.17-6.62) | 3.05 × 10−6 | 0.98 | Genotyped |
rs1989831 | 7 | 87205479 | T | 4.01 (2.24-7.17) | 2.87 × 10−6 | 0.98 | Imputed |
rs1989830 | 7 | 87205663 | A | 3.79 (2.17-6.62) | 3.05 × 10−6 | 0.99 | Genotyped |
rs1989829 | 7 | 87205707 | T | 3.79 (2.17-6.62) | 3.05 × 10−6 | 0.99 | Imputed |
rs1202177 | 7 | 87207914 | C | 3.79 (2.17-6.62) | 3.05 × 10−6 | 0.99 | Imputed |
rs1202176 | 7 | 87208987 | G | 3.79 (2.17-6.62) | 3.05 × 10−6 | 0.99 | Imputed |
rs1202175 | 7 | 87209150 | G | 3.79 (2.17-6.62) | 3.05 × 10−6 | 0.99 | Genotyped |
rs1202174 | 7 | 87209372 | T | 3.79 (2.17-6.62) | 3.05 × 10−6 | 0.99 | Imputed |
rs1202173 | 7 | 87210259 | A | 3.79 (2.17-6.62) | 3.05 × 10−6 | 1 | Imputed |
rs1202172 | 7 | 87210974 | C | 3.79 (2.17-6.62) | 3.05 × 10−6 | 1 | Imputed |
rs1202171 | 7 | 87211045 | T | 3.79 (2.17-6.62) | 3.05 × 10−6 | 1 | Genotyped |
rs1202186 | 7 | 87213258 | C | 3.79 (2.17-6.62) | 3.05 × 10−6 | 1 | Genotyped |
rs1202185 | 7 | 87213384 | C | 3.79 (2.17-6.62) | 3.05 × 10−6 | 1 | Genotyped |
rs1202182 | 7 | 87215304 | G | 3.79 (2.17-6.62) | 3.05 × 10−6 | 1 | Genotyped |
rs1202181 | 7 | 87216150 | G | 3.79 (2.17-6.62) | 3.05 × 10−6 | 1 | Genotyped |
rs1202180 | 7 | 87203840 | C | 3.57 (2.06-6.19) | 5.49 × 10−6 | 0.97 | Imputed |
rs1209054 | 7 | 87208225 | A | 3.91 (2.23-6.84) | 1.86 × 10−6 | 0.96 | Imputed |
rs1211151 | 7 | 87208255 | T | 3.79 (2.17-6.62) | 3.05 × 10−6 | 0.98 | Imputed |
rs28381820 | 7 | 87216216 | AAG | 3.79 (2.17-6.62) | 3.05 × 10−6 | 0.94 | Imputed |
Abbreviations: A1, allele 1, effect allele; CHR, chromosome; OR, per-allele odds ratio associated with effect allele; pCIA, persistent chemotherapy-induced alopecia; SNV, single-nucleotide variation.
Obtained in logistic regression analysis.
Pairwise correlation between the SNV (R2) and rs1202186.