Abbreviations	Definition
CNS	Central nervous system
DAMPs	Disease-associated molecular patterns
ATP	Adenosine triphosphate
UTP	Uridine triphosphate
GPCRs	G protein-coupled receptors
IP3	Inositol trisphosphate
Il-6	Interleukin-6
LPS	Lipopolysaccharides
Rac-1	Ras-related C3 botulinum toxin substrate 1
AKT	Protein kinase B
PC-PLC	Phosphatidylcholine-specific phospholipase C
PKC	Protein kinase C
tMCAO	Transient middle cerebral artery occlusion
Iba1	Ionized calcium-binding adaptor-1
Aβ	Amyloid-Beta
SNpc	Substantia nigra pars compacta
NP	Neuropathic pain
CCI	Chronic constriction injury
IHC	Immunohistochemistry
PAMPs	Pathogen associated molecular patterns
TLRs	Toll-like receptors
ADP	Adenosine diphosphate
UDP	Uridine diphosphate
PLC	Phospholipase C
IL-1	Interleukin-1
TNF-α	Tumor necrosis factor
TGF-β	Transforming growth factor-beta
M-CSF	Macrophage colony-stimulating factor
CMML	Chronic myelomonocytic leukemia
PI-PLC	Phosphoinositide-specific phospholipase C
ERK	Extracellular signal-regulated kinases
AD	Alzheimer’s disease
TUNEL	Terminal deoxynucleotidyl transferase dUTP nick end labeling
PD	Parkinson’s disease
MLCK	Myosin light chain kinase
SD	Sprague–Dawley
WB	Western blot
NMDG1	N-methyl-D-glucamine-1