Figure 6.

STL treatment elevated the levels of hydrogen peroxide and lipid peroxidation with concomitant reduction of the glutathione levels in PCSC. A. Determination of H₂O₂ levels using hydrogen peroxide assay upon treatment with STL for 6 hrs. Our data suggest that STL induces cell death mechanism by generating hydrogen peroxide levels in PCSC. B. Measurement of lipid peroxidation using TBARS assay of PCSC for 6 hrs which indicates that STL induces lipid peroxidation during cell death mechanism. C. Reduced levels of glutathione upon STL treatment for 6 hrs. The depleted levels of GSH indicates oxidative stress mediated by STL on PCSC. Data are means ± SD (n = 3). *P<0.05; **P<0.01 compared to control.