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. 2020 Jul 1;10(7):2083–2099.

Figure 5.

Figure 5

LMP1-induced NTRK2 promotes anoikis resistance through EMT. The NTRK2 inhibitor K252a (200 nM) was used to knock down NTRK2 activity in HM cells, and C666-1-shNTRK2 cells with NTRK2 stably knocked down were used. A. The expression of LMP1, NTRK2, E-cadherin and Vimentin was analyzed by western blot. B. The expression of E-cadherin, Vimentin, and cleaved PARP and caspase3 was analyzed by western blot. C. Cell morphology under a microscope is shown. D. The expression of E-cadherin and vimentin in HM and C666-1 cells was evaluated by immunofluorescence. Scale bar: 50 µm.