Skip to main content
. 2020 Jul 18;13(7):155. doi: 10.3390/ph13070155

Figure 1.

Figure 1

(A) Architecture of SARS-CoV-2 genome. The ORF1ab will be translated into two overlapping polyproteins, PP1a, consisting of NSP1-11, and PP1ab, consisting of NSP1-16, with the exception of NSP11, which is part of NSP12 in PP1ab. The rest of the ORFs encode the four structural proteins, S, E, M, and N, and several accessory proteins with unknown functions. (B) Structure of SARS-CoV-2 virion. The lipid bilayer. embedded with S, E, and M proteins, capsulizes the single-stranded genomic RNA, which is stabilized by the N protein. The S protein is responsible for the recognition of host cell ACE2 receptor to gain cell entry.