Table 2.

Exemplary mRNA targets of more than one UMD.

mRNA	NMD-Inducing Feature	2nd UMD	UMD-Inducing Feature
PTGS2	uORF	RMD	long structured 3′UTR
ATF3	uORF, PTC introduced by alternative splicing	RMD	long structured 3′UTR
GADD45B	3′UTR intron		long structured 3′UTR
COL22A1	PTC introduced by alternative splicing	RMD	long structured 3′UTR
PEA15	uORF	UPF1/SMG7/ miRNA-MD	miRNA seed sequence complementarity in 3′UTR
NFKBIB	PTC introduced by alternative splicing	RMD	long structured 3′UTR