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Schema of the effects of Semaphorin 3A (Sema3A) on DPSCs. In case of pulp exposure, DPSCs migrate toward the exposure site, then they proliferate and differentiate into odontoblasts to form reparative dentin. Sema3A can act as a bioactive agent to facilitate these regenerative processes. #, sealing material; *, Sema3A. The original data was published in [40].
