Table 1.
Baseline demographic values, comorbidities and outcomes of multicenter cohort with COVID-19
| (A) Baseline characteristics | COVID-19 (n = 101) | Severe (n = 74) | Non-severe (n = 27) | p valuea |
|---|---|---|---|---|
| Demographic values | ||||
| Age, median (IQR) | 66 (55–78) | 72 (58–80) | 53 (43–63) | < 0.001 |
| Women, n (%) | 49 (48.5) | 31 (41.9) | 18 (66.7) | 0.04 |
| Past vascular risk factors, n (%) | ||||
| Arterial hypertension | 61 (60.4) | 53 (71.6) | 8 (29.6) | < 0.001 |
| Hyperlipidemia | 27 (26.7) | 21 (28.4) | 6 (22.2) | 0.38 |
| Diabetes mellitus | 27 (26.7) | 24 (32.4) | 3 (11.1) | 0.04 |
| Atrial fibrillation | 18 (17.8) | 15 (20.3) | 3 (11.1) | 0.39 |
| Tobacco use | 13 (12.9) | 7 (9.5) | 6 (22.2) | 0.1 |
| Coronary heart disease | 14 (13.9) | 11 (14.9) | 3 (11.1) | 0.75 |
| Cerebrovascular disease | 16 (15.8) | 15 (20.3) | 1 (3.7) | 0.06 |
| Ischemic stroke | 13 (12.9) | 12 (16.2) | 1 (3.7) | |
| Transient ischemic attack | 2 (2) | 2 (2.7) | 0 | |
| Intracerebral hemorrhage | 1 (1) | 1 (1.4) | 0 |
| (B) Severity outcomes |
COVID-19 (n = 101) |
|||
| Disease severity by NHC, n (%) | ||||
| Mild/moderate | 27 (26.7) | |||
| Severe | 48 (47.5) | |||
| Critical | 26 (25.8) | |||
| Stages of disease by LEOSS, n (%) | ||||
| Uncomplicated | 28 (27.7) | |||
| Complicated | 46 (45.6) | |||
| Critical | 27 (26.7) | |||
| Recovery | 70 (69.3) | |||
| Intensive care treatment | 23 (22.8) | |||
| In-hospital death | 20/99 (20.2)b |
(A) The upper part of the table shows the distribution of demographic and vascular risk profiles among patients with severe versus non-severe COVID-19 as defined by the National Health Commission guideline with subsuming categories mild and moderate in a “non-severe” category and moderate and critical in a “severe “ category [10]
(B) The lower part of the table shows the distribution of severity outcomes within our cohort of COVID-19 patients
IQR interquartile range, NHC National Health Commission, LEOSS Lean European Open Survey on SARS CoV II Infected Patients
ap values refer to between-group comparisons
bAccording to patients discharged at the time of analysis