Table 3.
Vital signs and arterial blood gas analysis
| HR (bpm) | MAP (mmHg) | RR (bpm) | pH | PaCO2 (mmHg) | PaO2/FiO2 (mmHg) | |
|---|---|---|---|---|---|---|
| NIV (n = 42) | ||||||
| Baseline | 87.5 (80.8–101.5) | 84.5 ± 10.3 | 21 (16–26) | 7.45 (7.40–7.49) | 53 (48.8–61.3) | 229.3 ± 42.0 |
| 1 h | 90.5 (80–108.3) | 86.8 ± 10.2 | 25.5 (18–28)* | 7.44 (7.39–7.48) | 55 (48.8–61.3) | 218.9 ± 37.8* |
| 24 h | 94 (79.8–105.3) | 87.6 ± 11.1 | 24.5 (18–27)* | 7.45 (7.41–7.48) | 52.5 (49–57.3) | 222.4 ± 34.5 |
| 48 h | 93.5 (79.5–107.5) | 87.7 ± 12.6 | 21.5 (16.8–26) | 7.45 (7.41–7.48) | 52 (49–56) | 227.2 ± 40.5 |
| p valuea | 0.083 | 0.097 | 0.000 | 0.884 | 0.542 | 0.002 |
| HFNC (n = 44) | ||||||
| Baseline | 92 (80.5–107.8) | 88 ± 6.0 | 18 (16–23) | 7.48 (7.42–7.51) | 50.5 (48–57.8) | 239.2 ± 47.0 |
| 1 h | 94.5 (86–103.8) | 89.7 ± 7.9 | 21 (18–25)* | 7.42 (7.40–7.48)* | 56 (49.3–59)* | 220.5 ± 36.3* |
| 24 h | 93 (80.3–99.8) | 87.0 ± 8.8 | 20 (17.3–24.5)# | 7.44 (7.41–7.48) | 54 (49–58) | 228.4 ± 35.3 |
| 48 h | 92 (82.3–103.3) | 86.1 ± 8.1 | 19 (16.3–23.8) | 7.43 (7.41–7.49) | 51 (49–57.8) | 230.3 ± 36.0 |
| p valuea | 0.454 | 0.129 | 0.009 | 0.002 | 0.016 | 0.000 |
Data are shown as means ± standard deviation or median (interquartile range)
HFNC high-flow nasal cannula oxygen therapy, NIV non-invasive ventilation, HR heart rate, MAP mean arterial pressure, RR respiratory rate, PaCO2 partial pressure of arterial carbon dioxide, PaO2 partial pressure of arterial oxygen, FiO2 fraction of inspiration oxygen
*Compared with the baseline value in the same group, p < 0.05 after Bonferroni correction
#Compared with NIV at the same time point, p < 0.05
aComparison of multiple time points within the group