Table 2. CLN6 variants (transcript ENSFCAT00000025909) in cat whole genome sequences – 99 Lives^a.

Chr:Pos	Ref/Alt	Allele Counts	# Alleles	Allele Freq.	# Het	# Homo	Effect	Coding Change	Protein Change
B3:39320853	C/G	33	390	0.085	27	3	missense	c.71C > G	p.Ser24Cys
B3:39327181	G/A	49	390	0.126	23	13	missense	c.118G > A	p.Gly40Ser
B3:39331723	C/T	175	390	0.449	81	47	splice region	c.202-6C > T	———
B3:39331755	G/A	11	390	0.028	9	1	synonymous	c.228G > A	p.Pro76=
B3:39331770	C/T	1	390	0.003	1	0	synonymous	c.243C > T	p.Ser81=
B3:39331773	G/T	1	390	0.003	1	0	synonymous	c.246G > T	p.Val82=
B3:39331797	C/T	1	390	0.003	1	0	synonymous	c.270C > T	p.Tyr90=
B3:39331801	A/G	2	390	0.005	2	0	missense	c.274A > G	p.Ile92Val
B3:39331815	C/T	2	390	0.005	2	0	synonymous	c.288C > T	p.Phe96=
B3:39331818	T/C	2	390	0.005	2	0	synonymous	c.291T > C	p.Leu97=
B3:39332915	G/C	1	390	0.003	1	0	missense	c.339G > C	p.Met113Ile
B3:39332917	T/C	1	390	0.003	1	0	missense	c.341T > C	p.Ile114Thr
B3:39332918	C/G	1	390	0.003	1	0	missense	c.342C > G	p.Ile114Met
B3:39332935	C/T	1	390	0.003	1	0	missense	c.359C > T	p.Thr120Ile
B3:39332940	G/A	1	390	0.003	1	0	missense	c.364G > A	p.Val122Ile
B3:39336061	A/C	2	390	0.005	2	0	missense	c.794A > C	p.Tyr265Ser

^aData from 99 Lives Cat whole genome sequences annotated with Ensembl 97 (Jaffey et al. 2019).