Figure 3.

Changes of ¹³C-labeled metabolites in ipsilateral striatum after ethyl pyruvate (EP) and placebo treatment. Vasoconstriction of the medial cerebral artery (MCA) was induced by ET-1 infusion (150 pmol/15 µL/15 min) starting at time = 0 h. Blue symbols and line indicate data for rats treated with EP immediately after ET-1 infusion (n = 5). Red symbols and line indicate data for control rats (placebo treatment after ET-1, n = 6). Metabolite data are expressed as mean ± SEM of percentage change of each rat’s own baseline.