Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of events by which HMGB1 derived from endothelial cells, tissue macrophages and parenchymal cells at sites of chronic tissue injury may drive a chronic inflammatory response that potentially leads to the development of epithelial cell injury, oxidative/inflammatory damage to DNA and tumor promotion.
