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. 2020 Jul 7;13(7):144. doi: 10.3390/ph13070144

Figure 4.

Figure 4

Ectopic downregulation of miR-101-3p in breast cancer cells interferes with brain intercellular junctions.(A,C) Transendothelial electrical resistance (TEER) was measured for brain endothelial cells co-cultured with MDA-MB-231-TGL cells treated with negative control, miR-101-3p inhibitor and/or celecoxib (B) Western Blot analysis of VE-cadherin and claudin-5 protein expression was measured by Western blot in hCMEC/D3 co-cultured with MDA-MB-231-TGL cells treated with miR-101-3p inhibitor or control. Data are mean ±SD from three to six independent experiments. * p < 0.05, *** p < 0.001.