Figure 6.

Secoemestrin C treatment inhibits the production of serum proinflammatory cytokines in Con A-challenged mice. Serum was prepared from blood collected 8 h after Con A injection. Serum levels of IFN-γ (A), IL-2 (B), IL-6 (C), IL-17 (D), TNF-α (E), and IL-4 (F) were quantified by cytometric bead array kit. Bar graphs depict the concentrations of the indicated cytokines from the various groups. Values are presented as means ± SEM (six mice per group). **P<0.01 vs. the control (NC) group. #P<0.05 and ##P<0.01 vs. the Con A-treated group.