Figure 7.

Secoemestrin C rescues hepatic NKT decrease in Con A-challenged mice. C57BL/6J mice were sacrificed 8 h after being injected with Con A, and liver mononuclear cells (MNCs) were collected. The cells were stained with mAbs against TCRβ, CD4, CD8, or NK1.1, then analyzed by flow cytometry. A. Bar graphs depict the percentages of TCRβ⁺NK1.1⁺ NKT cells (NKT) vs. MNCs and of TCRβ⁺NK1.1^- conventional T cells (conT) vs. MNCs. B. Summary bar graphs display conventional CD4⁺ and CD8⁺ T cell (CD4⁺ conT and CD8⁺ conT) proportions in conventional T cells. Values shown are means ± SEM (five mice per group). ***P<0.001 vs normal the control (NC) group. ##P<0.01 vs. the Con A-treated group.