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Apatinib suppresses DOX-induced NF-κB activation. A. The cell extracts were analyzed for p65 and p50 levels by western blot analysis. B. Effect of DOX and apatinib on an NF-κB activity with NF-κB-dependant luciferase reporter assay. C. The mRNA levels were analyzed for IL-8 and survivin by quantitative PCR using specific primers. **P<0.01 vs the indicated group.
