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. 2020 Jul 15;12(7):3489–3500.

Figure 5.

Figure 5

Circ_BICD2 regulates Warburg effect induced by HK2 vis sponging miR-107 in OSCC cells. A and B. Western blot was used to detect the expression of HK2 in both SCC25 and Ca9-22 cells. C. The glucose uptake colorimetric assay kit was used to detect the levels of glucose uptake in both SCC25 and Ca9-22 cells. D. The lactate colorimetric assay kit was applied to measure the level of lactate production. E. The ATP colorimetric assay kit was performed to examine the level of ATP generation in both SCC25 and Ca9-22 cells. Data are presented as means ± SD of three independent experiments. **P<0.01, ***P<0.001, vs the control group; ##P<0.01, ###P<0.001, vs the si-HK2 group.