Figure 6.

Platelet PDGF can promote the invasion and metastasis of CCA in vivo. A. Representative photographs of liver metastasis foci in mice 45 days after splenic injection of RBE cells and platelet-stimulated RBE cells in the absence and presence of CP inhibitors (n=5 per group). Quantification of the numbers of liver metastatic foci is shown on the right. B. Representative images of metastatic foci (magnification, ×100 and ×400) in haematoxylin and eosin-stained liver tissue sections from mice injected with control or platelet-stimulated RBE cells in the absence and presence of CP inhibitors. **P<0.01.