Figure 1.

Differential expression of Apelin, APJ, and miR-424 in PCOS patients. A. Elevated expression of Apelin in serum from PCOS patients. Apelin concentration in human serum was determined by ELISA. B. Elevated expression of Apelin in follicular fluid collected from patients with PCOS. Apelin concentration in follicular fluids was measured by ELISA. C. Decreased miR-424 levels in granulosa cells (GCs) from follicular fluid of PCOS patients. D. Increased expression of APJ in GCs purified from follicular fluid in PCOS patients. PCOS: polycystic ovary syndrome; APJ: Apelin receptor; NOR: normal control; * indicates P < 0.05.