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. 2020 Jul 15;12(7):3895–3905.

Figure 2.

Figure 2

ECSW promotes the cell viability of EPCs and inhibits the apoptosis through the PI3K/AKT and MEK/ERK signaling pathways. A. Quantitative analysis of the cell viability of EPCs in each group. ECSW promoted the cell viability of EPCs while pretreatment with PI3K/AKT inhibitor LY294002 or MEK/ERK inhibitor PD98059 inhibited this effect. Data are presented as mean ± SD, N=5. *P<0.05 vs group vehicle, #P<0.05 vs group ECSW. B. The percentage of apoptotic cells with Annexin V-FITC positive expression was used to assess EPC apoptosis. ECSW protected EPCs from apoptosis while pretreatment with PI3K/AKT inhibitor LY294002 or MEK/ERK inhibitor PD98059 inhibited this effect of ECSW. Data are presented as mean ± SD, N=3. *P<0.05 vs group vehicle, #P<0.05 vs group ECSW. C. Cell apoptosis was detected by Annexin V-FITC and PI double staining and analyzed with flow cytometry.