Table 1.
List of commonly used antimicrobial classes and their pharmacokinetic-pharmacodynamic (PK-PD) indices.
| Class | PK-PD Index | Reference |
|---|---|---|
| Aminoglycosides | Cmax/MIC AUC0–24/MIC |
[40] |
| Beta-Lactams | fT > MIC | [41] |
| Fluoroquinolones | Cmax/MIC AUC0–24/MIC |
[33,42] |
| Glycopeptides | AUC0–24/MIC | [43] |
| Glycylcyclines | AUC0–24/MIC | [44,45] |
| Lincosamides | fT > MIC | [46] |
| Lipopeptides | Cmax/MIC AUC0–24/MIC |
[47] |
| Macrolides |
fT > MIC AUC0–24/MIC (azithromycin) |
[48,49] |
| Oxazolidinones |
fT > MIC AUC0–24/MIC |
[50] |
| Polymyxins | AUC0–24/MIC | [51] |
| Triazoles antifungals | AUC0–24/MIC | [52] |
| Echinocandins | AUC0–24/MIC Cmax/MIC |
[53] |
| Polyenes | Cmax/MIC | [54] |