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. 2020 Jul 12;12(7):658. doi: 10.3390/pharmaceutics12070658

Table 1.

Description of beta-cyclodextrin monomers and polymers studied in this work.

Cyclodextrin Code DS 1 MW 2 CLR 3 CD 4 Analogue Fluorescent Cyclodextrin
(2-Hydroxy-3-N,N,N-trimethyl
amino) propyl-beta-cyclodextrin chloride
QA 3 1589.8 3 RBITC-QA
Quaternary-ammonium-beta-cyclodextrin soluble polymer crosslinked with epichlorohydrin QAPS 2.2 40,000 ~11 2.2 RBITC-QAPS
Heptakis (6-deoxy-6-amino)-beta-cyclodextrin heptahydrochloride HA - 1383.3 7
Soluble amino-beta-cyclodextrin polymer crosslinked with epichlorohydrin HAPS 1 25,000 ~10 1
(2-Hydroxypropyl)-beta-cyclodextrin HP 4.5 1400 RBITC-HP
Soluble β-cyclodextrin polymer crosslinked with epichlorohydrin PS - 92,000 ~11 RBITC-PS

1 DS: Average Degree of Substitution; 2 MW: Average Molecular Weight (g/mol); 3 CLR: Cross-Linking Ratio (mol epichlorohydrin /mol CD); 4 CD: Cationic Density (cationic groups per cyclodextrin unit).