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. 2020 Jul 2;9(7):149. doi: 10.3390/biology9070149

Table 1.

Inhibitory activity of RNF, RNF1, RNF3L and some ranacyclins against trypsin, chymotrypsin and tryptase.

Peptide Peptide Sequence Ki(µM) of Trypsin Ki(µM) of Chymotrypsin Ki(µM) of Tryptase
RNF GAPRGCWTKSYPPQPCF-NH2 0.447 N.I. 6.774
RNF1 GAPRGCWTKSYPPQPCF 1.300 N.I. 9.059
RNF3L GALRGCWTKSYPPQPCF-NH2 0.201 N.I. 12.5
Ranacyclin-T [10] GALRGCWTKSYPPKPCK 0.116 - -
HJTI [31] GAPKGCWTKSYPPQPCS-NH2 0.388 - -
OSTI [24] AALKGCWTKSIPPKPCF-NH2 0.0003 N.I. 2.5
PPF-BBI [32] ALRGCWTKSIPPKPCP-NH2 0.17 N.I. 30.73

N.I., there was no inhibitory activity; -, there was no mention in previous studies.