Table 3.

Some parameters of RNF and some reported ranacyclins and their trypsin inhibition Ki values. Amino acid residues at P5′ are shaded.

Peptide	Peptide Sequence	Net Charge	Trypsin Inhibition Ki (nM)
RNF	GAPRGCWTKSYPPQPCF-NH2	3	447
Ranacyclin-T [10]	GALRGCWTKSYPPKPCK-NH2	5	116
HJTI [31]	GAPKGCWTKSYPPQPCS-NH2	3	388
OSTI [24]	AALKGCWTKSIPPKPCF-NH2	4	0.3
PPF-BBI [32]	ALRGCWTKSIPPKPCP-NH2	4	170