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. 2020 Jul 5;10(7):1001. doi: 10.3390/biom10071001

Figure 3.

Figure 3

Alb-Sch B co-therapy inhibits inflammasome activation and pyroptosis in A. cantonensis-infected mice. (A) RNA transcription levels of inflammasome components, including NLRC4, NLRP1B, Caspase-1, IL-18, IL-1β, and gasdermin D (GSDMD),were measured by qPCR. Data are presented as the mean ± SD (n = 5). (B) Representative western blot images reflecting protein levels ofinflammasome components. (C) Bar graphs showing protein expression levels relative to that of α-tubulin. Results are presented as the mean ± SD (n = 3). (D) Lactate dehydrogenase (LDH)levels measured in the cerebrospinal fluid (CSF), shown as the mean ± SD (n = 5). * p-value < 0.05, ** p-value < 0.01, *** p-value < 0.001, and **** p-value < 0.0001.