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. 2020 Jun 28;9(7):1573. doi: 10.3390/cells9071573

Figure 2.

Figure 2

NK cell activation and IFN-γ and TNF-α production were enhanced by Cetuximab opsonization of IIB-BR-G cells. NK cells were co-cultured with IIB-BR-G cells opsonized with IC or Cetuximab, in the absence (NK) or presence of DCs (DCs+NK), in a DCs:NK:IIB-BR-G ratio of 1:1:1 for 24 h. (A) Representative histograms showing CD25, CD69 and HLA-DR expression in NK cells after co-cultures in the presence of DCs. (B) Expression of CD25, CD69 and HLA-DR in NK cells (n = 3–6). Bars with different letters are statistically different, p < 0.05 (ANOVA). (C) IFN-γ and TNF-α concentration in the co-culture supernatants (n = 3–4).