Table 2.

Examples of microbiota-based therapeutic strategies and development phase (not intended to be exhaustive).

Microbiota Based Therapies		Symptomatology		Trials	Reference
Bacteriophages	Muddy, BPs33ΔHTH-HRM10, and ZoeJΔ45	Cystic fibrosis	Mycobacterial infection	Clinical case study	[90]
	OMKO1	Prosthetic vascular graft infections	Pseudomonas aeruginosa	Preclinical	[91]
	PP1131 cocktail	Burn wounds infected	Pseudomonas aeruginosa	Phase I-II	[92]
	Myoviridae	Enteric infection	Escherichia coli	Preclinical	[93]
	phage cocktail	Burn wound infections	Klebsiella pneumoniae	Preclinical	[94]
FMT		Clostridium difficile		Preclinical	[95]
		Ulcerative colitis		Phase II	[96]
				Phase II	[97]
Probiotics	Lactobacillus acidophilus Saccharomyces boulardii Lactococcus lactis, Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus reuteri, Lactobacillus plantarum, Bifidobacterium infantis	Traveler’s diarrhea, Antibiotic-associated diarrhea, Ulcerative colitis Crohn’s disease, Atopic dermatitis, Clostridium difficile Irritable bowel syndrome		Phase II	[98,99,100,101]