Figure 1.

Basophils in ovarian cancer patient blood. CCR3^highSSC^low basophils identified in unfractionated whole blood by flow cytometry (A,B), express FcεRI, some of which carry endogenous receptor-bound IgE antibodies (C). Basophil populations (gated in circle) were not impacted by prior chemotherapy (D), prior treatment history or time since last chemotherapy (−/+ treatment previously received or not); (E) or elevated serum tryptase (F). Recent prolonged high-dose oral corticosteroids were associated with a marked depletion of basophil populations (gated in circle) (G). ns = not significant; ** = p ≤ 0.01.