Table 1.

Sample input to FLUTE

Regulated	Regulated type	Regulated ID	Regulator	Regulator type	Regulator ID	Effect	Reference	Evidence (sentence segment)
apoptosis	biological process	GO:0006915	Fas	protein	P25445	increases	PMC149420	‘Cell lines resistant to Fas mediated apoptosis…’
beta-catenin	protein	P35222	Axin	protein	O15169	decreases	PMC4102778	‘A complex is formed consisting of and APC, Axin, beta-catenin …’
GSK-3beta	protein	P49841	sorafenib	chemical	216 239	increases	PMC4102778	‘The multi-kinase inhibitor sorafenib induced GSK-3beta…’

Each row corresponds to one event extracted from literature using machine reading.

The type of the regulator and regulated element, along with the standardized IDs, are used to find support in databases.