Table 3.
Queries: different topic categories, example query terms for each topic category and the corresponding query expressions entered in PubMed
| # | Query topic category | Query terms | Query expression |
|---|---|---|---|
| 1 | Disease | Breast cancer | ‘breast cancer’ |
| 2 | Cellular process | DNA repair | ‘DNA repair’ |
| 3 | Signaling pathway | MAPK/ERK pathway | ‘erk pathway’ or ‘mapk pathway’ or ‘ras pathway’ |
| 4 | Protein | BRCA1 | BRCA1 |
| 5 | Chemical | Progesterone | Progesterone |
| 6a | Disease and process | Breast cancer, DNA repair | ‘breast cancer’ and ‘dna repair’ |
| 6b | Autophagy, cancer | autophagy and cancer | |
| 7 | Disease and pathway | Breast cancer, MAPK/ERK pathway | ‘breast cancer’ and (‘erk pathway’ or ‘mapk pathway’ or ‘ras pathway’) |
| 8 | Disease and protein | Breast cancer, BRCA1 | ‘breast cancer’ and brca1 |
| 9 | Disease and chemical | Breast cancer, progesterone | ‘breast cancer’ and progesterone |
| 10a | Process and protein | DNA repair, BRCA1 | ‘dna repair’ and brca1 |
| 10b | ADAM17, inflammation | ADAM17 and inflammation | |
| 11a | Well studied | EGFR | EGFR |
| 11b | HER2 | her2 | |
| 12 | New discovery | copb2* | copb2 |
| 13a | Multiple aliases | RSK90 | ‘rsk 90’ |
| 13b | RPS6KA1 | ||
| 13c | RSK-1 | ||
| 13d | S6K | ||
| 14a | Non-standard characters | Beta catenin | CTNNB1 |
| 14b | ‘Beta catenin’ | ||
| 14c | Beta-catenin | ||
| 14d | CTNNB | ||
| 15a | Different gene and | Estrogen receptor | ‘Estrogen Receptor 1’ |
| 15b | Protein name | ESR1 | |
| 15c | ER | ||
| 16a | Same gene and | PTEN | Pten |
| 16b | Protein name | GRB2 | GRB2 |