Table 2. IC50 Values for the Inhibitory Activities of Compound 6b toward VEGFR-2, PDGFR, and C-Met Kinases.
| IC50 (nM) |
|||
|---|---|---|---|
| compound | VEGFR-2 | PDGFR | C-Met |
| 6b | 435 | 371 | 654 |
| sunitinib | 346 | 304 | 468 |
| IC50 (nM) |
|||
|---|---|---|---|
| compound | VEGFR-2 | PDGFR | C-Met |
| 6b | 435 | 371 | 654 |
| sunitinib | 346 | 304 | 468 |