Figure 5.

The effects of cardiac NMDAR modulation in preC and postC on NO₂⁻ and O₂⁻. (A,E) preconditioned with glutamate and TG; (B,F) preconditioned with memantine and MK-801; (C,G) postconditioned with glutamate and TG; (D,H) postconditioned with memantine and MK-801. NO₂⁻—nitrites; O₂⁻—superoxide anion radical; TG—(RS)-(Tetrazol-5-yl)glycine; preC—preconditioning; postC—postconditioning. Some results regarding the effects of MK-801 on oxidative balance have been partially published [30] as a preliminary report. Statistical significance between points of interest was presented as: a—in control group; b—in glutamate group; c—in TG group; d—in memantine group; e—in MK-801 group. Statistical significance was considered significant if the p value was less than 0.05 (p < 0.05).