Table 1.
Baseline Characteristics (n = 164) | Mean (SD) or % |
---|---|
Age at prescription of IA, years | 65.7 (14.4) |
Gender Male/Female | 47%/53% |
BMI, kg/m2 | 24.5 (4.7) |
Years since diagnosis of BE | 12.8 (11.4) |
Post-infectious aetiology | 33% |
Idiopathic | 26% |
Associated COPD | 37% |
Associated asthma | 20.6% |
Active smoker | 3.8% |
Accumulated packs/year | 17 (32.4) |
Dyspnoea (mMRC) | 1.5 (1.1) |
Cough prior to prescription of IA | 83.8% |
Common mucopurulent or purulent sputum | 57.5% |
Quantity > 30 mL/day | 31.6% |
FEV1, % pred | 52.2 (20.7) |
Number of lobes affected | 2.99 (1.4) |
Presence of cystic BE | 28.7% |
CBI by PA | 86% |
CBI by other PPM | 29.4% |
FACED score | 3.7 (1.6) |
Mild BE (0–2 points) | 21.2% |
Moderate BE (3–4 points) | 50.7% |
Severe BE (5–7 points) | 28.1% |
E-FACED score | 4.7 (2.1) |
Isolation of fungi | 18.2% |
Isolation of NTM | 7.4% |
Nº exacerbations in the year prior to the prescription of IA | 1.9 (1.9) |
Nº hospitalisations in the year prior to the prescription of IA | 0.73 (1.25) |
IA: Inhaled antibiotics; BMI: Body Mass Index; BE: bronchiectasis; COPD: Chronic Obstructive Pulmonary Disease; mMRC: Modified Medical Research Council; FEV1: Forced expiratory volume in 1 s; CBI: Chronic Bronchial Infection; PPM: Potentially Pathogenic Microorganism; FACED: (F) FEV1, (A) Age (C) Chronic colonization, (E) Extension, (D) Dyspnoea; E-FACED: FACED plus exacerbations; NTM: Non-tuberculous mycobacterium; IA: Inhaled antibiotics; PPM: Potentially Pathogenic Microorganism; CBI: Chronic Bronchial Infection.