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Mismatch repair. Simplified scheme of mismatch repair of DNA mismatches or insertion/deletions mispairs (gene alternations in OvC in bold) [111]. Protein names: MutS homolog 2 (MSH2), MutS homolog 3 (MSH3), MutS homolog 6 (MSH6), MutL homolog 1 (MLH1), PMS1 homolog 1 (PMS1), PMS1 homolog 2 (PMS2), MutL homolog 3 (MLH3), replication protein A (RPA), exonuclease 1 (EXO1), replication factor C subunit 1 (RFC1), DNA polymerase delta (POLD), DNA ligase 1 (LIG1) [44].
