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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Brain Behav Immun. 2019 Aug 30;82:302–308. doi: 10.1016/j.bbi.2019.08.198

Table 1.

Characteristics of study population

Characteristics Non-
asthmatic
mothers
(N=877,936)
Asthmatic mothers
All asthmatic
mothers
(N=83,266)
No
exacerbations
(N=69,746)
With
exacerbations
before pregnancy
only (N=7,573)
With
exacerbations
during pregnancy
(N=2,103)
With
exacerbations
after delivery
(N=3,844)
Maternal age at delivery (years)
 25 111,758 (12.7) 13,050 (15.7) 11,076 (15.9) 1,136 (15.0) 305 (14.5) 533 (13.9)
 25–34 614,502 (70.0) 56,050 (67.3) 47,012 (67.4) 5,094 (67.3) 1,302 (61.9) 2,642 (68.7)
≥>35 151,676 (17.3) 14,166 (17.0) 11,658 (16.7) 1,343 (17.7) 496 (23.6) 669 (17.4)
Parity
 1 380,386 (43.3) 36,530 (43.9) 30,831 (44.2) 3,392 (44.8) 819 (38.9) 1,488 (38.7)
 ≥2 493,723 (56.2) 46,296 (55.6) 38,555 (55.3) 4,136 (54.6) 1,270 (60.4) 2,335 (60.7)
 Unknown 3,827 (0.4) 440 (0.5) 360 (0.5) 45 (0.6) 14 (0.7) 21 (0.6)
Maternal smoking during pregnancy
 Yes 146,268 (16.7) 17,540 (21.1) 14,573 (20.9) 1,607 (21.2) 506 (24.1) 854 (22.2)
 No 705,865 (80.4) 63,497 (76.3) 53,359 (76.5) 5,755 (76.0) 1,522 (72.4) 2,861 (74.4)
 Unknown 25,803 (2.9) 2,229 (2.7) 1,814 (2.6) 211 (2.8) 75 (3.6) 129 (3.4)
Maternal mental disorder before pregnancy
 No mental disorder 731,199 (83.3) 59,216 (71.1) 50,287 (72.1) 4,975 (65.7) 1,339 (63.7) 2,615 (68.0)
 ADHD 1,108 (0.1) 367 (0.4) 309 (0.4) 28 (0.4) 10 (0.5) 20 (0.5)
 Other mental disorders 145,629 (16.6) 23,683 (28.4) 19,150 (27.5) 2,570 (33.9) 754 (35.9) 1,209 (31.5)
Maternal cohabiting status
 Married or cohabiting 773,997 (88.2) 71,590 (86.0) 60,045 (86.1) 6,465 (85.4) 1,744 (82.9) 3,336 (86.8)
 Single, divorced, or widow 95,348 (10.9) 11,446 (13.7) 9,498 (13.6) 1,097 (14.5) 351 (16.7) 500 (13.0)
 Unknown 8,591 (1.0) 230 (0.3) 203 (0.3) 11 (0.2) 8 (0.4) 8 (0.2)
Place of residence at delivery
 Capital or capital suburb 258,780 (29.5) 22,844 (27.4) 19,386 (27.8) 1,864 (24.6) 664 (31.6) 930 (24.2)
 Provincial city or town 345,904 (39.4) 33,107 (39.8) 27,575 (39.5) 3,129 (41.3) 791 (37.6) 1,612 (41.9)
 Rural areas 273,252 (31.1) 27,315 (32.8) 22,785 (32.7) 2,580 (34.1) 648 (30.8) 1,302 (33.9)
Low social class at delivery
Yes 85,382 (9.7) 10,602 (12.7) 8,687 (12.5) 1,042 (13.8) 353 (16.8) 520 (13.5)
No 764,450 (87.1) 71,626 (86.0) 60,243 (86.4) 6,434 (85.0) 1,695 (80.6) 3,254 (84.7)
Missing 28,104 (3.2) 1,038 (1.3) 816 (1.2) 97 (1.3) 55 (2.6) 70 (1.8)
Large family size at delivery
Yes 40,573 (4.6) 4,384 (5.3) 3,493 (5.0) 475 (6.3) 175 (8.3) 241 (6.3)
No 837,363 (95.4) 78,882 (94.7) 66,253 (95.0) 7,098 (93.7) 1,928 (91.7) 3,603 (93.7)
Calendar year of birth
 1997–2000 238,719 (27.2) 14,008 (16.8) 11,381 (16.3) 1,432 (18.9) 437 (20.8) 758 (19.7)
 2001–2005 276,070 (31.4) 23,709 (28.5) 19,584 (28.1) 2,279 (30.1) 634 (30.2) 1,212 (31.5)
 2006–2012 363,147 (41.4) 45,549 (54.7) 38,781 (55.6) 3,862 (51.0) 1,032 (49.1) 1,874 (48.8)
Paternal asthma before delivery 59,890 (6.8) 7,274 (8.7) 6,102 (8.8) 647 (8.5) 202 (9.6) 323 (8.4)
Sex of the child
 Boys 427,372 (48.7) 40,560 (48.7) 33,972 (48.7) 3,733 (49.3) 1,021 (48.5) 1,834 (47.7)
 Girls 450,564 (51.3) 42,706 (51.3) 35,774 (51.3) 3,840 (50.7) 1,082 (51.5) 2,010 (52.3)
Preterm birth (gestational age <37 weeks)
 Yes 41,472 (4.7) 4,725 (5.7) 3,827 (5.5) 481 (6.4) 173 (8.2) 244 (6.3)
 No 836,464 (95.3) 78,541 (94.3) 65,919 (94.5) 7,092 (93.6) 1,930 (91.8) 3,600 (93.7)
Low birth weight (<2500 g)
 Yes 30,790 (3.5) 3,462 (4.2) 2,808 (4.0) 355 (4.7) 120 (5.7) 179 (4.7)
 No 847,146 (96.5) 79,804 (95.8) 66,938 (96.0) 7,218 (95.3) 1,983 (94.3) 3,665 (95.3)

Figures are numbers (%).