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. Author manuscript; available in PMC: 2020 Aug 6.
Published in final edited form as: Pediatr Blood Cancer. 2017 Aug 12;65(1):10.1002/pbc.26757. doi: 10.1002/pbc.26757

Figure 1.

Figure 1.

Complications in pregnancies with affected offspring. *P<0.01 (A) Fanconi anemia: Children with ≥3 physical malformations consistent with VACTERL-H phenotype (Red bars) had significantly more perinatal complications (P=0.001), non-reassuring fetal status (fetal distress) (P=0.003) and cesarean delivery for complications (P=0.001) than in those with 0-2 malformations (Blue bars). SGA and preterm birth occurred with similar frequency in children with ≥3 or 0-2 malformations. B) Dyskeratosis congenita: Offspring with Hoyeraal-Hreidarsson syndrome or Revesz syndrome (Red bars) had significantly more complications (P<0.0001), fetal distress (P<0.0001), SGA (P<0.0001), preterm birth (P=0.004) and cesarean delivery for complications (P<0.0001) than those with other dyskeratosis congenita types (Blue bars). C) Diamond Blackfan anemia: Affected offspring with anemia at birth (Red bars) had significantly more complications (P<0.0001), fetal distress (P<0.0001), preterm birth (P=0.004) and cesarean delivery for complications (P=0.001) than those without anemia (Blue bars) while the frequency of SGA was similar.