Table 1.
LC-ESI-MS | UHPLC-FLD | MALDI-FTICR-MS | ||||
---|---|---|---|---|---|---|
Dataset Name | Korčula 2013 | Korčula 2010 | Split | Vis | CRC Controls | LLS |
Glycans measured | IgG Fc | IgG Fc | IgG Fc | IgG Fc | IgG total | Total plasma |
Number of peaks | 50 | 50 | 50 | 50 | 24 | 61 |
Number of samples for analysis | 669 | 504 | 980 | 395 | 535 | 2056 |
Age range (mean ± SD) |
18–88 (53.2 ± 16.3) |
18–98 (56.4 ± 13.6) |
18–85 (50.3 ± 14.3) |
18–91 (55.8 ± 15.2) |
21–74 (51.6 ± 5.9) |
30–80 (59.2 ± 6.7) |
LC-ESI-MS: Liquid Chromatography-ElectroSpray Ionization-Mass Spectrometry; UHPLC-FLD: Ultra High Performance Liquid Chromatography with Fluorescence Detection; MALDI-FTICR-MS: Matrix Assisted Laser Desorption Ionization-Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry; CRC: Colorectal cancer; LLS: Leiden Longevity Study; IgG: Immunoglobulin G; Fc: Fragment crystallizable; SD: standard deviation.