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. 2020 Jul 8;9(7):1640. doi: 10.3390/cells9071640

Figure 4.

Figure 4

Effect of inflammation on ADHLSC mRNA expression profile. (A) Differential modulation of ADHLSC gene expression profile by 24 h inflammation. (B) Differential modulation of ADHLSC gene expression profile by 9-days inflammation. RT-qPCR gene expression analysis demonstrated that inflammation differentially modulated the mRNA expression pattern of several ADHLSC genes. Differences in the upregulated and downregulated genes are observed between 24 h and 9 days of inflammatory treatment. For the ADHLSC treated group, results are expressed as mRNA relative expression versus untreated cells. CD54 (Intercellular Adhesion Molecule 1; ICAM-1), Sox9 (SRY-Related HMG-Box 9 encoding gene), Snail (SNAI1), Slug (SNAI2), COL1alpha1 (collagen type 1 alpha 1), VIM (Vimentin), and ALB (Albumin). Data shown are the mean ± SEM of three independent experiments (three samples from different donors). *** denotes a p value < 0.001; ** p < 0.01; * p < 0.05 vs. corresponding control, paired Student’s t-test.