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Bile acid composition analyzed in mouse plasma and liver tissue samples. Data represent relative abundances (%). The four groups correspond to control, and simvastatin exposure in mice at three different doses: 5, 10, and 25 mg/kg/day. (A,C) Profiles of free bile acids in plasma and liver tissue, respectively; (B,D) Taurine-conjugated bile acids in plasma and liver, respectively. n = 6 per group.
