Table 1.
Combining the Skeletal Muscle-Specific Proteome with the Core Transcriptional Signature from HypAt that Covaried with Gains in Muscle Mass across 3 Independent Studies Identified the Majority of Known Canonical Regulations of Cell Hypertrophy from Model Systems
| Pathway | FDR |
|---|---|
| FOXO signaling | 3E−14 |
| MAPK signaling | 3E−10 |
| Neurotrophin signaling | 1E−9 |
| Mitophagy | 6E−9 |
| HIF-1 signaling | 5E−8 |
| Longevity regulating pathway | 2E−7 |
| AMPK signaling | 3E−7 |
| Hippo signaling | 9E−7 |
| PI3K-Akt signaling | 1E−6 |
| Apelin signaling | 1E−6 |
| Adipocytokine signaling | 2E−6 |
FDR is −log value. FDR, false discovery rate.