Figure 1.

Comparison of the Cytosponge-TFF3 procedure with the endoscopy procedure

(A) Administration and passage of the Cytosponge-TFF3 device to obtain a sample of oesophageal epithelial cells. (B) Administration and passage of an endoscope to visualise the oesophagus. The Cytosponge-TFF3 sample is processed to a paraffin block and stained with an antibody against (C) TFF3 and with (D) haematoxylin and eosin (magnification × 200). (E) Endoscopic white light view of Barrett's oesophagus in deep red compared with surrounding light pink squamous epithelium. (F) One or more endoscopic biopsies are taken and the tissues are stained with haematoxylin and eosin for histopathological assessment (magnification × 200). (A) and (B) were drawn by Campbell Medical Illustration (Glasgow, Scotland). TFF3=trefoil factor 3.