Table 2.

Barrett's oesophagus diagnoses in the usual care group compared with the intervention group

	Usual care group (n=6388)	Intervention group (n=6834)	Absolute difference in rates per 1000 person-years (95% CI)	Overall rate ratio (95% CI); p value	Adjusted rate ratios (95% CI); p value
					Cluster randomised group	Patient-level randomised group	Overall*
Number of participants diagnosed with Barrett's oesophagus	13 (<1%)	140 (2%)†	..	..	..	..	..
Follow-up, person-years	6579	6952	..	..	..	..	..
Rate of Barrett's oesophagus, per 1000 person-years	2·0	20·2‡	18·3 (14·8–21·8)	10·2 (5·8–18·1)	10·0 (5·0–20·0); p<0·0001	12·0 (4·3–33·2); p<0·0001	10·6 (6·0–18·8); p<0·0001

Data are n (%), unless otherwise specified.

^*Overall adjusted rate ratio is a combined rate ratio of the two randomisation groups (cluster randomisation and individual patient-level randomisation) and accounts for clustering.

^†Number of participants diagnosed with Barrett's oesophagus in the intervention group includes all participants who were offered the Cytosponge procedure.

^‡The rate of Barrett's oesophagus in the intervention group was calculated as the weighted average of the rate in the first 4 months of follow-up and the rate in the following months, with a weight ratio of 1:2.